S’alrighty, I got the go ahead to take binimetinib, and (better yet) at the same dose as before. This is good news as my elevated creatine kinase represented a Grade 2 adverse event, in the parlance of trials. There was a distinct possibility that my dose would have been reduced or even that I would have been disqualified from the trial. Just another garden variety close call.
My eyes checked out ok today as well. My biggest issue per vision is not the (mild) retinopathy, but rather the fact that my eyes are so friggin dry. Like the inside of my mouth and the tips of my fingers. Even the acne that I may develop as a side effect is related to dryness. Lubricate, lubricate, lubricate!
Tomorrow is going to be a long day of pharmacokinetics, but I shall be happy to be there. Hopefully from this point forward side effects will be manageable and better yet, maybe I’ll have some response.
In the meantime, I just ordered some condoms or finger sleeves. Party!